TY  - JOUR
AU  - Benjamin Rey, Claude Duchamp
PY  - 2017//
TI  - Uncoupling effect of palmitate is exacerbated in skeletal muscle mitochondria of sea-acclimatized king penguins (Aptenodytes patagonicus)
KW  - Bioenergetics Birds Free fatty acids Mitochondria Muscle
N2  - In king penguin juveniles, the environmental transition from a terrestrial to a marine habitat, occurring at fledging, drastically stimulates lipid catabolism and the remodelling of muscle mitochondria to sustain extensive swimming activity and thermoregulation in the cold circumpolar oceans. However, the exact nature of these mechanisms remains only partially resolved. Here we investigated, in vitro, the uncoupling effect of increasing doses of fatty acids in pectoralis muscle intermyofibrillar mitochondria isolated, either from terrestrial never-immersed or experimentally cold water immersed pre-fledging king penguins or from sea-acclimatized fledged penguins. Mitochondria exhibited much greater palmitate-induced uncoupling respiration and higher maximal oxidative capacity after acclimatization to marine life. Such effects were not reproduced experimentally after repeated immersions in cold water, suggesting that the plasticity of mitochondrial characteristics may not be primarily driven by cold exposure per se but by other aspects of sea acclimatization.
SN  - 1095-6433
SN  - 1095-6433
UR  - http://dx.doi.org/10.1016/j.cbpa.2017.06.009
N1  - exported from refbase (http://publi.ipev.fr/polar_references/show.php?record=7225), last updated on Sat, 06 Jul 2024 05:57:15 +0200
ID  - BenjaminRey2017
ER  -