TY  - JOUR
AU  - Pierre Bl&eacute
AU  - vin, Fr eacute
AU  - d&eacute
AU  - ric Angelier, Sabrina Tartu
AU  - phanie Ruault, Paco Bustamante
AU  - rge Moe, Claus Bech
PY  - 2016//
TI  - Exposure to oxychlordane is associated with shorter telomeres in arctic breeding kittiwakes
T2  - 0048-9697
JO  - SCIENCE OF THE TOTAL ENVIRONMENT
SP  - 125–130
VL  - 563–564
N2  - Telomeres are DNA-protein complexes located at the end of chromosomes, which play an important role inmaintaining the genomic integrity. Telomeres shorten at each cell division and previous studies have shown that telomere length is related to health and lifespan and can be affected by a wide range of environmental factors. Among them, some persistent organic pollutants (POPs) have the potential to damage DNA. However, the effect of POPs on telomeres is poorly known for wildlife. Here, we investigated the relationships between some legacy POPs (organochlorine pesticides and polychlorobiphenyls) and telomere length in breeding adult blacklegged kittiwakes (Rissa tridactyla), an arctic seabird species. Our results show that among legacy POPs, only blood concentration of oxychlordane, the major metabolite of chlordane mixture, is associatedwith shorter telomere length in females but not in males. This suggests that female kittiwakes could be more sensitive to oxychlordane, potentially explaining the previously reported lower survival rate in most oxychlordanecontaminated kittiwakes from the same population. This study is the first to report a significant and negative relationship between POPs and telomere length in a free-living bird and highlights sex-related susceptibility to banned pesticides.
SN  - 0048-9697
UR  - http://dx.doi.org/10.1016/j.scitotenv.2016.04.096
N1  - exported from refbase (http://publi.ipev.fr/polar_references/show.php?record=6441), last updated on Mon, 01 Jul 2024 20:28:38 +0200
ID  - PierreBl&eacute_etal2016
ER  -