TY  - JOUR
AU  - Keyser Christine, Hollard Clémence
PY  - 2015//
TI  - The ancient Yakuts: a population genetic enigma.
JO  - Philosophical transactions of the Royal Society of London. Series B, Biological sciences
SP  - 20130385
VL  - 370
IS  - 1660
KW  - Base Sequence
KW  - Bone and Bones
KW  - Bone and Bones: chemistry
KW  - Chromosomes
KW  - Human
KW  - Y
KW  - Y: genetics
KW  - DNA
KW  - Mitochondrial
KW  - Mitochondrial: genetics
KW  - Mitochondrial: history
KW  - Ethnic Groups
KW  - Ethnic Groups: genetics
KW  - Ethnic Groups: history
KW  - Fossils
KW  - Genetics
KW  - Population
KW  - Haplotypes
KW  - Haplotypes: genetics
KW  - History
KW  - 15th Century
KW  - 16th Century
KW  - 17th Century
KW  - 18th Century
KW  - 19th Century
KW  - Humans
KW  - Likelihood Functions
KW  - Male
KW  - Microsatellite Repeats
KW  - Microsatellite Repeats: genetics
KW  - Molecular Sequence Data
KW  - Pedigree
KW  - Polymorphism
KW  - Single Nucleotide
KW  - Single Nucleotide: genetics
KW  - Sequence Analysis
KW  - Siberia
KW  -
N2  - This study is part of an ongoing project aiming at determining the ethnogenesis of an eastern Siberian ethnic group, the Yakuts, on the basis of archaeological excavations carried out over a period of 10 years in three regions of Yakutia: Central Yakutia, the Vilyuy River basin and the Verkhoyansk area. In this study, genetic analyses were carried out on skeletal remains from 130 individuals of unknown ancestry dated mainly from the fifteenth to the nineteenth century AD. Kinship studies were conducted using sets of commercially available autosomal and Y-chromosomal short tandem repeats (STRs) along with hypervariable region I sequences of the mitochondrial DNA. An unexpected and intriguing finding of this work was that the uniparental marker systems did not always corroborate results from autosomal DNA analyses; in some cases, false-positive relationships were observed. These discrepancies revealed that 15 autosomal STR loci are not sufficient to discriminate between first degree relatives and more distantly related individuals in our ancient Yakut sample. The Y-STR analyses led to similar conclusions, because the current Y-STR panels provided the limited resolution of the paternal lineages.
SN  - 1471-2970
UR  - http://dx.doi.org/10.1098/rstb.2013.0385
N1  - exported from refbase (http://publi.ipev.fr/polar_references/show.php?record=6240), last updated on Sat, 06 Jul 2024 07:14:39 +0200
ID  - KeyserChristine2015
ER  -