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GEOFFROY L. (2005). Volcanic passive margins.337, 1395–1409.
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Alix C. (2004). Etudes/Inuits/Studies, 28, 109–132.
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Nicolas, M., Weiss, K., & Heas, S. (2006). Inflexions, 3, 183–198.
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Tafforin, C. (2006). Human Ethology Bulletin, 21(4).
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Marx J.C., Poncin J., Simorre J.P., Ramteke P.W. & Feller, G. (2008). The non-catalytic triad of alpha-amylases: a novel structural motif involved in conformational stability. Proteins: Structure, Function, and Bioinformatics, 70(2). Retrieved July 9, 2024, from http://dx.doi.org/10.1002/prot.21594
Abstract: Chloride-activated alpha-amylases contain a noncatalytic triad, independent of the glycosidic active site, perfectly mimicking the catalytic triad of serine-proteases and of other active serine hydrolytic enzymes. Mutagenesis of Glu, His, and Ser residues in various alpha-amylases shows that this pattern is a structural determinant of the enzyme conformation that cannot be altered without losing the intrinsic stability of the protein. 1H-15N NMR spectra of a bacterial alpha-amylase reveal proton signals that are identical with the NMR signature of catalytic triads and especially a deshielded proton involving a protonated histidine and displaying properties similar to that of a low barrier hydrogen bond. It is proposed that the H-bond between His and Glu of the noncatalytic triad is an unusually strong interaction, responsible for the observed NMR signal and for the weak stability of the triad mutants. Furthermore, a stringent template-based search of the Protein Data Bank demonstrated that this motif is not restricted to alpha-amylases, but is also found in 80 structures from 33 different proteins, amongst which SH2 domain-containing proteins are the best representatives.
Programme: 193
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Collins T., D'Amico S., Marx J., Feller G. & Gerday C. (2007). Cold-Adapted Enzymes. Bachelor's thesis, , .
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Bailleul F., Charrassin J.B., Monestiez P., Roquet F., Biuw M., Guinet C. (2007). Successful foraging zones of southern elephant seals from Kerguelen Islands in relation to oceanographic conditions. Philos. Trans. R. Soc. Lond., B, Biol. Sci., 362, 2169–2181.
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Cafarella L., Di Mauro D., Lepidi S., Meloni A., Pietrolungo M., Santarelli L. & Schott J.J. (2007). Daily variation at Concordia station (Antarctica) and its dependence on IMF conditions. Annali di Geofisica – Ann Geofisc, 25.
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Peri, A. Bachelard, C. Cazes, G. & Paty, B. (2006). Giornale di medicina militare, .
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Biuw M., Boehme L., Guinet C., Hindell M., Costa D., Charrassin J.B., Roquet F., Bailleul F., Meredith M., Thorpe S, Tremblay Y, McDonald B., Park Y.-H., Rintoul S., Bindoff N., Goebel M., Crocker D., Lovell P., Nicholson J., Monks F., Fedak M. (2007). Variations in behaviour and condition of a Southern Ocean top predator in relation to in-situ oceanographic conditions. Proc. Natl. Acad. Sci. U.S.A., 104, 13705–13710.
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